Extended in vitro expansion

Extended in vitro expansion induces chromosomal and subchromosomal abnormalities in humans.

“diverse culture conditions and extended in vitro expansion inevitably give rise to chromosomal and subchromosomal abnormalities.”

Reviewin vitro culture

Genomic stability of human pluripotent stem cells: advances in research and screening criteria

Stem cells translational medicine·7 Apr 2026