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Excess body weight

Exposure

2 papers2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 2 countries
  • Funders: National Cancer Institute and 3 more
  • Humans1
  • In silico1

Associations

2

Cancer

upin humans1

1 study

  1. Excess body weight raises the risk of cancer in humans.

    “The incidence of 11 EBW-related cancers has increased from 1990 to 2021.”

    Humans1990 to 2021

    Global cancer burden attributable to excess body weight, 1990 to 2021, decomposed by population size, aging, and epidemiological change

    Obesity (Silver Spring, Md.)Feb 20, 2025

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Renal cell cancer

upin humans1HR 1.49

1 study

  1. Excess body weight raises the risk of renal cell cancer in humans (HR, 1.49; 95% CI, 1.19-1.87).

    “we observed an increased hazard of RCC for BMI trajectory of progressing from normal BMI to overweight [HR, 1.49; 95% confidence interval (CI), 1.19-1.87]”

    Humansprogressing from normal BMI to overweight vs retaining normal BMI throughout adulthood

    Lifetime Body Weight Trajectories and Risk of Renal Cell Cancer: A Large U.S. Prospective Cohort Study

    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyAug 25, 2023

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