Renal cell cancer
2 papers3 findings
- Humans2
Associations
3Weight gain
upin humans1
1 study
Weight gain
upin humans1
Weight gain raises the risk of renal cell cancer in humans (≥10 kg weight gain).
“Weight gain of ≥10 kg was associated with increased RCC incidence for each age span.”
Humansduring each age span≥10 kg
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyAug 25, 2023
Obesity
upin humans1HR 2.22
1 study
Obesity
upin humans1HR 2.22
Obesity raises the risk of renal cell cancer in humans (HR, 2.22; 95% CI, 1.70-2.90).
“from normal BMI to obesity (HR, 2.22; 95% CI, 1.70-2.90)”
Humansprogressing from normal BMI to obesity vs retaining normal BMI throughout adulthood
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyAug 25, 2023
Excess body weight
upin humans1HR 1.49
1 study
Excess body weight
upin humans1HR 1.49
Excess body weight raises the risk of renal cell cancer in humans (HR, 1.49; 95% CI, 1.19-1.87).
“we observed an increased hazard of RCC for BMI trajectory of progressing from normal BMI to overweight [HR, 1.49; 95% confidence interval (CI), 1.19-1.87]”
Humansprogressing from normal BMI to overweight vs retaining normal BMI throughout adulthood
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive OncologyAug 25, 2023
Trial sponsors
Novartis Pharmaceuticals Corporation
Company1 trialPhase 450 people
1 trialPhase 454 people
University of Kansas Medical Center
1 trialPhase 225 people
Case Comprehensive Cancer Center
1 trialPhase 217 people
2 trialsPhase 1/2131 people
University of Southern California
1 trialPhase 1/250 people
Funding
1 grant since 2025National Cancer InstituteUS$131.1k