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Eudesmin

Intervention

1 paper3 findings

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

3

P38/JNK MAPK signaling

downin mouse cells1

1 study

  1. Eudesmin inhibits P38/JNK MAPK signaling in mouse cells.

    “Mechanistically, we discovered that EDN inhibited the P38/JNK MAPK pathway in aging cells.”

    Cellsaging cellsMIN6

    Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

    Experimental gerontology15 Nov 2024

Cellular senescence

downin mice1

1 study

  1. Eudesmin decreases cellular senescence in mice.

    “the YY1 agonist eudesmin (EDN) improved glucose intolerance in mice, alleviated aging of pancreatic beta cells”

    AnimalsD-gal-induced mouse model of pancreatic agingpancreatic beta cell

    Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

    Experimental gerontology15 Nov 2024

More on Cellular senescence

Impaired glucose tolerance

downin mice1

1 study

  1. Eudesmin decreases impaired glucose tolerance in mice.

    “the YY1 agonist eudesmin (EDN) improved glucose intolerance in mice”

    AnimalsD-gal-induced mouse model of pancreatic aging

    Identifying and validating the key regulatory transcription factor YY1 in the aging process of pancreatic beta cells based on bioinformatics

    Experimental gerontology15 Nov 2024

More on Impaired glucose tolerance

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