Estrogen + progestin therapy

Estrogen + progestin therapy has been studied in 4 papers since 2021: none in people yet, 4 reviews. No study of it in people or animals has been published yet. The newest paper, Sep 26, 2024: “Menopause and endometriosis”.

Intervention

4 papers study it2 findingsUpdated

See all 4 papers on estrogen + progestin therapy

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“Meta-analyses suggested a small increased AD risk after 5-10 years prescription of combination MHT regardless of age”
Alzheimer's Disease and (Phyto) Estrogen Treatment: Modification of Effects by Age, Type of Treatment, and Duration of UseJournal of Alzheimer's disease : JAD2024doi:10.3233/jad-231415
Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country

What is estrogen + progestin therapy linked with?

2

Studies link estrogen + progestin therapy with 2 measures, most often Alzheimer's disease (1 study) and breast cancer (1).

Alzheimer's disease

upin humans1

1 study
  1. Estrogen + progestin therapy is linked with a higher risk of Alzheimer's disease in humans (prescription of combination MHT regardless of age).

    “Meta-analyses suggested a small increased AD risk after 5-10 years prescription of combination MHT regardless of age”

    Humansprescription of combination MHT regardless of age5-10 yearsfemales

    Alzheimer's Disease and (Phyto) Estrogen Treatment: Modification of Effects by Age, Type of Treatment, and Duration of Use

    Journal of Alzheimer's disease : JAD

More on Alzheimer's disease

Breast cancer

upin humans1OR 1.14–2.38

1 study
  1. Estrogen + progestin therapy raises the risk of breast cancer in humans (OR 1.14- 2.38).

    “use of estrogen in combination with progestogens, depending on the type of progestogens, shows an increased risk of breast cancer”

    Reviewin combination with progestogens3 to 5 yearsfemales

    Progestins and the Risk of Breast Cancer

    Acta endocrinologica (Bucharest, Romania : 2005)

More on Breast cancer

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