Sleep
Estrogen acts in a brain region to reduce sleep in female rats
Experiments in adult female rats with ovaries removed identified a site where estradiol, a form of estrogen, altered sleep and wakefulness.Experiments in adult female rats with ovaries removed identified a site where estradiol, a form of estrogen, altered sleep and wakefulness.
Rat studyMechanisms
Who was studiedAdult female ovariectomized Sprague–Dawley rats
What changedEstradiol-treated female rats spent about 50 more minutes awake during the dark phase than at baseline
The catchInfusions could spread outside the median preoptic nucleus, so other regions could drive the effects