Equol + resveratrol

Intervention

2 papers study it6 findings

Across all fields, 2 papers: 2 trials in people

  • 1 lab in 1 country
  • Human trial2

Outcomes

6

Tartrate-resistant acid phosphatase 5b

no changein humans1

1 study
  1. Equol + resveratrol has no effect on tartrate-resistant acid phosphatase 5b in humans (p = 0.051).

    “Conversely, TRACP-5b levels were unaffected by supplementation (p = 0.051).”

    Human trial12 monthsfemalesn = 60

    Equol and Resveratrol Improve Bone Turnover Biomarkers in Postmenopausal Women: A Clinical Trial

    International journal of molecular sciences

More on Tartrate-resistant acid phosphatase 5b

Osteocalcin

upin humans1

1 study
  1. Equol + resveratrol improves osteocalcin in humans (p < 0.0001).

    “DPD, osteocalcin, and BAP significantly improved in the active group (p < 0.0001 for all) compared to the placebo group.”

    Human trial12 monthsfemalesn = 60

    Equol and Resveratrol Improve Bone Turnover Biomarkers in Postmenopausal Women: A Clinical Trial

    International journal of molecular sciences

More on Osteocalcin

Bone mineral density

upin humans1

1 study
  1. Equol + resveratrol increases bone mineral density in humans (p = 0.0220).

    “the intervention significantly increased BMD measured in the whole body (p = 0.0220) compared with the placebo.”

    Human trial12 monthsfemalesn = 60

    Equol and Resveratrol Improve Bone Turnover Biomarkers in Postmenopausal Women: A Clinical Trial

    International journal of molecular sciences

More on Bone mineral density

Sleep quality

upin humans1

1 study
  1. Equol + resveratrol improves sleep quality in humans (p<0.001).

    “Subjects treated with equol and resveratrol also had significant differences in the sleep domain of the NHP (p<0.001).”

    Human trialmenopausal women with hot flashes, anxiety and depressive symptomstablet200mg fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day)12 weeksfemalesn = 60

    Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study

    Maturitas

Depressive symptoms

downin humans1

1 study
  1. Equol + resveratrol decreases depressive symptoms in humans (-94.1% (p<0.001)).

    “On the HAM-D significant improvements at week 12 were seen in work and activities (-94.1%) (p<0.001).”

    Human trialmenopausal women with hot flashes, anxiety and depressive symptomstablet200mg fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day)12 weeksfemalesn = 60

    Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study

    Maturitas

More on Depressive symptoms

Vaginal dryness

downin humans1

1 study
  1. Equol + resveratrol decreases vaginal dryness in humans (-85.7% (p<0.001)).

    “Comparison between placebo and treatment groups revealed statistically significant improvement in particular for dryness of vagina (-85.7%) (p<0.001)”

    Human trialmenopausal women with hot flashes, anxiety and depressive symptomstablet200mg fermented soy containing 10mg of equol and 25mg of resveratrol (1 tablet/day)12 weeksfemalesn = 60

    Influence of equol and resveratrol supplementation on health-related quality of life in menopausal women: A randomized, placebo-controlled study

    Maturitas

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