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Elastin-derived fragments

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Humans1

Outcomes

1

Lifespan

downin mice1

1 study

  1. Elastin-derived fragments shorten lifespan in mice.

    “Elastin-derived fragments exhibited the most potent lifespan-shortening effects in mice”

    Animals

    Elastin-derived extracellular matrix fragments drive aging through innate immune activation

    Nature aging29 Sep 2025

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