Early-life psychosocial stress
1 paper2 findings
- 1 lab in 1 country
- Funders: National Heart, Lung, and Blood Institute and 3 more
- 2 of 2 findings with company ties
- Humans1
Outcomes
1Racial disparity in biological aging
mediatesin humans1
1 study
Racial disparity in biological aging
mediatesin humans1
Early-life psychosocial stress mediates racial disparity in biological aging in humans (22% of the disparity; p = .01).
“Mediation analysis indicated that early-life stress accounted for 22% of the racial disparity in biological aging (p = .01).”
HumansStatistical mediation of differences between Black and White Americansexposures during the first 20 years of lifen = 470
Impact of psychosocial stress in early life on pace of aging in young adulthood
Clinical epigenetics10 Nov 2025
Associations
1DunedinPACE
upin humans1
1 study
DunedinPACE
upin humans1
Early-life psychosocial stress is associated with DunedinPACE in humans (β = 0.25, 95% CI 0.159–0.335).
“WQS analysis revealed a positive joint effect of early life psychosocial stress on DunedinPACE (β = 0.25, 95% CI: 0.159-0.335)”
Humansperipheral bloodexposures during the first 20 years of lifen = 470
Impact of psychosocial stress in early life on pace of aging in young adulthood
Clinical epigenetics10 Nov 2025
Latest
1 in 12 monthsClinical Epigenetics
Impact of psychosocial stress in early life on pace of aging in young adulthood
Cohort study of 470 peoplePopulations