Dynapenic abdominal obesity
Dynapenic abdominal obesity has been studied in 8 papers since 2017: 8 observational studies in people; 5 in the past year. The newest paper, Jul 21, 2026: “Gender differences in the relationship between dynapenic abdominal obesity and non-neoplastic digestive system diseases among middle-aged and older adults”.
8 papers study it12 findingsUpdated
See all 8 papers on dynapenic abdominal obesity
At a glance
The findings reach people, from one lab or study. 7 independent labs in 4 countries.
“with the strongest association observed for PPC-MM [OR = 2.475 (1.100-5.002) in CHARLS; OR = 5.712 (2.009-14.882) in HRS]”
1 of its findings points the other way.
- 7 independent labs in 4 countries
- 1 finding against
- Funders: National Institute on Aging and 8 more
- Humans8
What did studies of dynapenic abdominal obesity find?
3Studies of dynapenic abdominal obesity measured 3 outcomes; the most studied are non-neoplastic digestive system diseases (1 study), progression from PC-MM to PPC-MM (1) and incident/worsening multimorbidity trajectories (1).
Non-neoplastic digestive system diseases
no changein humans1
1 study
Non-neoplastic digestive system diseases
no changein humans1
Dynapenic abdominal obesity was not clearly linked with non-neoplastic digestive system diseases in humans (compared with non-dynapenic/non-abdominally obese group).
“whereas no significant association was identified among men”
Humanscompared with non-dynapenic/non-abdominally obese groupmales
BMC gastroenterology
Progression from PC-MM to PPC-MM
upin humans1
1 study
Progression from PC-MM to PPC-MM
upin humans1
Dynapenic abdominal obesity is linked with higher progression from PC-MM to PPC-MM in humans (transition probabilities from continuous-time Markov multi-state models).
“an elevated probability of progressing from PC-MM to complex PPC-MM”
Humanstransition probabilities from continuous-time Markov multi-state modelsup to 4 years
Environmental health and preventive medicine
Incident/worsening multimorbidity trajectories
upin humans1
1 study
Incident/worsening multimorbidity trajectories
upin humans1
Dynapenic abdominal obesity is linked with higher incident/worsening multimorbidity trajectories in humans (longitudinal transitions; RRR reported separately for CHARLS and HRS) (RRR = 2.001, P = 0.014 in CHARLS; RRR = 2.507, P = 0.013 in HRS).
“D/AO was associated with a higher likelihood of entering "incident/worsening" trajectories”
Humanslongitudinal transitions; RRR reported separately for CHARLS and HRSup to 4 years
Environmental health and preventive medicine
What is dynapenic abdominal obesity linked with?
9Studies link dynapenic abdominal obesity with 9 measures, most often non-neoplastic digestive system diseases (1 study), symptomatic knee osteoarthritis (1) and cognitive impairment (1).
Non-neoplastic digestive system diseases
upin humans1HR 1.597
1 study
Non-neoplastic digestive system diseases
upin humans1HR 1.597
Dynapenic abdominal obesity is linked with a higher risk of non-neoplastic digestive system diseases in humans (compared with non-dynapenic/non-abdominally obese group; overall population) (HR 1.597, 95% CI 1.121-2.276).
“participants with DAO exhibited a significantly higher risk of NNDSD than those in the ND/NAO group (HR = 1.597, 95% CI: 1.121-2.276)”
Humanscompared with non-dynapenic/non-abdominally obese group; overall population
BMC gastroenterology
Symptomatic knee osteoarthritis
upin humans1
1 study
Symptomatic knee osteoarthritis
upin humans1
Dynapenic abdominal obesity is associated with symptomatic knee osteoarthritis in humans after adjustment for potential confounders.
“DAO is associated with an increased likelihood of symptomatic KOA, with dynapenia playing a more prominent role than abdominal obesity alone.”
Humansafter adjustment for potential confoundersn = 7,418
Annals of joint
Cognitive impairment
upin humans1
1 study
Cognitive impairment
upin humans1
Dynapenic abdominal obesity is associated with cognitive impairment in humans (type 2 diabetes).
“DAO is independently associated with cognitive impairment and presents phenotypic features linked to age and diabetes”
Humanstype 2 diabetesn = 270
International journal of endocrinology
PP-MM
upin humans1OR 6.98
1 study
PP-MM
upin humans1OR 6.98
Dynapenic abdominal obesity is linked with a higher risk of PP-MM in humans (age modifies the association; higher risk in HRS) (OR 6.98, 95% CI 1.85–26.31).
“PP-MM in HRS: OR = 6.98, 95% CI: 1.85-26.31”
Humansage modifies the association; higher risk in HRSup to 4 years
Environmental health and preventive medicine
PPC-MM
upin humans1OR 2.475
1 study
PPC-MM
upin humans1OR 2.475
Dynapenic abdominal obesity is linked with a higher risk of PPC-MM in humans (OR 2.475 (1.100-5.002) in CHARLS; OR 5.712 (2.009-14.882) in HRS).
“with the strongest association observed for PPC-MM [OR = 2.475 (1.100-5.002) in CHARLS; OR = 5.712 (2.009-14.882) in HRS]”
Humanscompared with the non-dynapenic/non-abdominal obesity group; CHARLS and HRS analyzed separatelyup to 4 years
Environmental health and preventive medicine
Falls
upin humans1HR 3.595
1 study
Falls
upin humans1HR 3.595
Dynapenic abdominal obesity is linked with a higher risk of falls in humans (HR 3.595 (95% CI 1.317-9.815)).
“D/AO was associated with a higher risk of falls (hazard ratio: 3.595 [95% CI: 1.317-9.815], even after adjustments”
Humansafter adjustment for age, body mass index, physical activity level, regular medication use, peripheral sensation, chronic diseases and lower-limb pain18 monthsfemalesn = 201
Dynapenic abdominal obesity and the incidence of falls in older women: a prospective study
Aging clinical and experimental research
Single fall
upin humans1
1 study
Single fall
upin humans1
Dynapenic abdominal obesity is associated with single fall in humans (RRR 2.06, 95% CI 1.04-4.10).
“Abdominal obesity (RRR=1.90 95% CI: 1.02-3.55), dynapenia (RRR=1.80 95% CI: 1.02-3.19), and dynapenic-abdominal obesity (RRR=2.06 95% CI: 1.04-4.10) were associated with a single fall.”
Humansn = 1,046
Abdominal obesity, dynapenia and dynapenic-abdominal obesity as factors associated with falls
Brazilian journal of physical therapy
Hospitalization
upin humans1
1 study
Hospitalization
upin humans1
Dynapenic abdominal obesity is linked with a higher risk of hospitalization in humans (compared with nondynapenic nonabdominal obese participants) (1.36 (95% CI 1.04-1.78)).
“significantly higher risk of hospitalization (1.36; 95% CI: 1.04-1.78) compared with ND/NAO participants”
Humanscompared with nondynapenic nonabdominal obese participants11-year follow-up
The journals of gerontology. Series A, Biological sciences and medical sciences
Worsening disability
upin humans1OR 2.1
1 study
Worsening disability
upin humans1OR 2.1
Dynapenic abdominal obesity is linked with a higher risk of worsening disability in humans (compared with nondynapenic nonabdominal obese participants) (OR 2.10 (95% CI 1.14-3.88)).
“D/AO participants presented more than a twofold increase in risk of worsening disability (odds ratio = 2.10; 95% confidence interval [CI]: 1.14-3.88)”
Humanscompared with nondynapenic nonabdominal obese participants11-year follow-up
The journals of gerontology. Series A, Biological sciences and medical sciences