DNA methylation-based epigenome editing

DNA methylation-based epigenome editing has been studied in 1 paper since 2026: none in people yet, 1 in cells; 1 in the past year. No study of it in people or animals has been published yet. The newest story, Nov 5, 2026: “Gene silencing lasts and partly reverses in human blood stem cells”.

Intervention

1 paper studies it1 findingUpdated Nov 1, 2026

1 new paper in 30 daysSee all 1 papers on DNA methylation-based epigenome editing

At a glance

The findings reach cells, none yet in people. 1 lab.

1 lab

Funders: Howard Hughes Medical Institute and 1 more

Cells1

What did studies of DNA methylation-based epigenome editing find?

Studies of DNA methylation-based epigenome editing measured 1 outcome; the most studied are heritable gene silencing (1 study).

Heritable gene silencing

upin human cells1

1 study

DNA methylation-based epigenome editing induces heritable gene silencing in human cells.
“DNA methylation-based epigenome editors delivered transiently as RNA induce heritable gene silencing in primary human HSCs.”
CellsRNAhematopoietic stem cell
Gene silencing lasts and partly reverses in human blood stem cells
Cell stem cellNov 1, 2026

Latest

1 paper in 12 months

Cell Stem CellNov 5

Gene silencing lasts and partly reverses in human blood stem cells

Silencing of a platelet-related gene remained stable four months after human stem cells were transplanted into mice.Silencing of a platelet-related gene remained stable four months after human stem cells were transplanted into mice.

Human cell studyInterventions

Paper