Diphenyl diselenide + swimming exercise

Diphenyl diselenide + swimming exercise has been studied in 1 paper since 2016: none in people yet, 1 in animals. The research so far is in animals. The newest paper, May 20, 2016: “A diphenyl diselenide-supplemented diet and swimming exercise promote neuroprotection, reduced cell apoptosis and glial cell activation in the hypothalamus of old rats”.

Intervention

1 paper studies it3 findingsUpdated

  • 1 lab in 1 country
  • Funders: Conselho Nacional de Desenvolvimento Científico e Tecnológico and 3 more
  • Animals1

What did studies of Diphenyl diselenide + swimming exercise find?

3

Studies of Diphenyl diselenide + swimming exercise measured 3 outcomes; the most studied are mature BDNF and NeuN (1 study), apoptosis (1) and glial cell activation (1).

Mature BDNF and NeuN

upin rats1

1 study
  1. Diphenyl diselenide + swimming exercise increases mature BDNF and NeuN in rats.

    “The levels of mBDNF and NeuN, but not the pAkt/Akt ratio, were increased by combined treatment.”

    Animalsold Wistar ratshypothalamus4 weeksmales

    A diphenyl diselenide-supplemented diet and swimming exercise promote neuroprotection, reduced cell apoptosis and glial cell activation in the hypothalamus of old rats

    Experimental gerontology

More on Mature BDNF and NeuN

Apoptosis

downin rats1

1 study
  1. Diphenyl diselenide + swimming exercise decreases apoptosis in rats.

    “a (PhSe)2-supplemented diet and swimming exercise promoted neuroprotection in the hypothalamus of old rats, reducing apoptosis and glial cell activation.”

    Animalsold Wistar ratshypothalamus4 weeksmales

    A diphenyl diselenide-supplemented diet and swimming exercise promote neuroprotection, reduced cell apoptosis and glial cell activation in the hypothalamus of old rats

    Experimental gerontology

More on Apoptosis

Glial cell activation

downin rats1

1 study
  1. Diphenyl diselenide + swimming exercise decreases glial cell activation in rats.

    “Old rats that received a (PhSe)2-supplemented diet and performed swimming exercise had the hypothalamic levels of Iba-1 and GFAP decreased.”

    Animalsold Wistar ratshypothalamus4 weeksmales

    A diphenyl diselenide-supplemented diet and swimming exercise promote neuroprotection, reduced cell apoptosis and glial cell activation in the hypothalamus of old rats

    Experimental gerontology

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