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Dietary live microbes

Exposure

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 1 country
  • Funders: National Natural Science Foundation of China and 2 more
  • Humans2

Outcomes

1

PhenoAgeAccel

downin humans1

1 study

  1. Dietary live microbes decrease PhenoAgeAccel in humans (β = -0.15; 95% CI: -0.26 to -0.04; P = 0.008).

    “Higher intake of live dietary microbes, compared to lower intake, was associated with a slower rate of accelerated aging after full adjustment for confounders”

    Humansn = 4,909

    The association between dietary live microbes intake and PhenoAge in US non-diabetes adults and the mediating effect of insulin resistance: NHANES 2007-2018

    Aging clinical and experimental research17 Jun 2025

More on PhenoAgeAccel

Associations

2

PhenoAge

downin humans1

1 study

  1. Dietary live microbes lower the risk of PhenoAge in humans (25% (95% CI: 4% to 42%) reduced risk).

    “and a 25% (95% CI: 4% to 42%) reduced risk of PA acceleration.”

    Humanshigh vs low dietary live microbe intaken = 7,719

    Higher dietary intake of live microbes is inversely associated with accelerated biological aging

    Food & function10 Feb 2025

More on PhenoAge

KDM-BA acceleration

downin humans1

1 study

  1. Dietary live microbes lower the risk of KDM-BA acceleration in humans (20% (95% CI: 2% to 35%) reduced risk).

    “those in the high dietary live microbe intake group had a 20% (95% CI: 2% to 35%) reduced risk of KDM-BA acceleration”

    Humanshigh vs low dietary live microbe intaken = 7,719

    Higher dietary intake of live microbes is inversely associated with accelerated biological aging

    Food & function10 Feb 2025

More on KDM-BA acceleration

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