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Dicretin

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: European Foundation for the Study of Diabetes and 6 more
  • Animals1

Outcomes

3

Insulin resistance

downin mice1

1 study

  1. Dicretin decreases insulin resistance in mice.

    “Markers of glucose tolerance and insulin resistance improved in all treatment groups.”

    Animalsin diet-induced obese mice24 days

    Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJun 10, 2024

Glucose tolerance

upin mice1

1 study

  1. Dicretin improves glucose tolerance in mice.

    “Markers of glucose tolerance and insulin resistance improved in all treatment groups.”

    Animalsin diet-induced obese mice24 days

    Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJun 10, 2024

Hepatic steatosis

downin mice1

1 study

  1. Dicretin decreases hepatic steatosis in mice.

    “Dicretin lead to superior reduction of hepatic lipid content when compared to Semaglutide or equivalent weight loss by calorie restriction.”

    Animalsin diet-induced obese mice24 days

    Chronic treatment with glucagon-like peptide-1 and glucagon receptor co-agonist causes weight loss-independent improvements in hepatic steatosis in mice with diet-induced obesity

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJun 10, 2024

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