Depletion of fapα+ macrophages

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Medical Science and Technology Project of Zhejiang Province and 2 more
  • Animals1

Outcomes

1

Efficacy of anti-PD-1/PD-L1 antibody therapy

upin mice1

1 study
  1. Depletion of fapα+ macrophages improve efficacy of anti-PD-1/PD-L1 antibody therapy in mice.

    “depletion of FAPα+ macrophages significantly boosted the efficacy of anti-PD-1/PD-L1 antibody therapy”

    Animalsin MM mouse models

    FAPα⁺ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD-L1 and T Cell Senescence

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)30 Jan 2026

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