Dc hyperactivator
1 paper2 findings
- 1 lab in 1 country
- Funders: Charles A. King Trust and 5 more
- Animals1
Outcomes
2Anti-tumor CD4+ T cells persisting into old age
upin mice1
1 study
Anti-tumor CD4+ T cells persisting into old age
upin mice1
Dc hyperactivator induces anti-tumor CD4+ T cells persisting into old age in mice.
“DC hyperactivators were the only adjuvant identified that elicited anti-tumor CD4+ T cells that persisted into old age.”
AnimalsCD4+ T cell
Correction of age-associated defects in dendritic cells enables CD4⁺ T cells to eradicate tumors
Cell12 Jun 2024
dendritic cell migration
upin mice1
1 study
dendritic cell migration
upin mice1
Dc hyperactivator improves dendritic cell migration in mice.
“We identified a vaccine adjuvant, referred to as a DC hyperactivator, which corrects DC migratory defects in the elderly.”
Animalsdendritic cell
Correction of age-associated defects in dendritic cells enables CD4⁺ T cells to eradicate tumors
Cell12 Jun 2024