Papers on dasatinib + quercetin
394 papers8 new in 30 days
Tuesday, April 26
Saturday, April 23
GeroScience
Senolytic treatment reverses obesity-mediated senescent cell accumulation in the ovary
Experiments in miceSenolytics
Tuesday, April 19
Saturday, April 16
The Journal of Clinical Investigation
Age-associated callus senescent cells produce TGF-β1 that inhibits fracture healing in aged mice
Experiments in miceBone fracture
Frontiers in Pharmacology
A Human Conditionally Immortalized Proximal Tubule Epithelial Cell Line as a Novel Model for Studying Senescence and Response to Senolytics
Experiments in human cellsSenolytics
Wednesday, April 6
Research Square
Targeting senescent cells by dasatinib and quercetin ameliorates postmenopausal osteoporosis and rejuvenates bone regeneration
Preprint: experiments in ratsDasatinib + quercetin
Wednesday, March 30
PLOS One
Identification of gingerenone A as a novel senolytic compound
Experiments in human cellsSenolytics
Friday, March 25
GeroScience
Senolytic treatment rescues blunted muscle hypertrophy in old mice
Experiments in miceSenolytics
Thursday, March 17
EBioMedicine
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Experiments in miceSenolytics
Sunday, March 6
Journal of Bone and Mineral Research
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence
Experiments in miceBone loss
Wednesday, February 16
Scientific Reports
Dasatinib plus quercetin attenuates some frailty characteristics in SAMP10 mice
Experiments in miceDasatinib + quercetin
Thursday, February 3
Tuesday, February 1
The Journal of Prevention of Alzheimer's Disease
Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD): A Pilot Clinical Trial
Thursday, January 20
Saturday, January 15
Female Pelvic Medicine & Reconstructive Surgery
Induction of Cellular Senescence in Rat Vaginal Fibroblasts and Treatment With Senolytics: An in Vitro Model for the Study of Pelvic Organ Prolapse
Experiments in rat cellsInterventions
Wednesday, December 15
Aging Cell
Deletion of SA β-Gal+ cells using senolytics improves muscle regeneration in old mice
Experiments in miceSenolytics
Sunday, November 28
International Journal of Molecular Sciences
Enhancement of Bone-Forming Ability on Beta-Tricalcium Phosphate by Modulating Cellular Senescence Mechanisms Using Senolytics
Experiments in ratsSenolytics
Wednesday, November 24
Cell Metabolism
Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity
Experiments in miceInsulin resistance
Wednesday, October 27
Mechanisms of Ageing and Development
Strategies for late phase preclinical and early clinical trials of senolytics
ReviewSenolytics
Friday, October 8
Tuesday, October 5
Analytical Chemistry
Aging Diagnostic Probe for Research on Aging and Evaluation of Anti-aging Drug Efficacy
Experiments in miceBiomarkers
Tuesday, September 14
Nature
Virus-induced senescence is a driver and therapeutic target in COVID-19
Experiments in miceCOVID-19
Saturday, September 11
Wednesday, September 8
bioRxiv
Roles of cellular senescence in driving bone marrow adiposity in radiation- and aging-associated bone loss
Preprint: experiments in miceBone loss
Friday, September 3
Nature Communications
Long-term treatment with senolytic drugs Dasatinib and Quercetin ameliorates age-dependent intervertebral disc degeneration in mice
Experiments in miceSenolytics
Wednesday, August 18
Current Molecular Biology Reports
Cellular Senescence in Idiopathic Pulmonary Fibrosis
ReviewCellular senescence
Saturday, July 31
Biochemical and Biophysical Research Communications
Senolytic treatment modulates decidualization in human endometrial stromal cells
Experiments in human cellsInterventions
Friday, June 18
Journal of the American Society of Nephrology
Progressive Cellular Senescence Mediates Renal Dysfunction in Ischemic Nephropathy
Experiments in miceRenal dysfunction
Sunday, June 13
NPJ Regenerative Medicine
Senolytics improve bone forming potential of bone marrow mesenchymal stem cells from aged mice
Experiments in miceSenolytics