D-malic acid

Intervention

1 paper3 findings

PubChemChEBI

  • 1 lab in 1 country
  • Funders: Guangdong Province Introduction of Innovative R&D Team and 3 more
  • Animals1

Outcomes

3

Angiogenesis

downin mouse cells1

1 study
  1. D-malic acid inhibits angiogenesis in mouse cells.

    “DMA decreases the proliferation of vascular endothelial cells and suppresses the formation of blood vessels.”

    Cellsin vitro

    Microbiota derived D-malate inhibits skeletal muscle growth and angiogenesis during aging via acetylation of Cyclin A

    EMBO reports22 Jan 2024

More on Angiogenesis

Muscle strength

downin mice1

1 study
  1. D-malic acid impairs muscle strength in mice.

    “resulting in reduced muscle mass, strength, and the number of blood vessels, as well as the skeletal muscle fiber type I/IIb ratio.”

    Animalsdietary supplementation2%

    Microbiota derived D-malate inhibits skeletal muscle growth and angiogenesis during aging via acetylation of Cyclin A

    EMBO reports22 Jan 2024

Muscle mass

downin mice1

1 study
  1. D-malic acid decreases muscle mass in mice.

    “dietary supplementation of 2% DMA inhibits metabolism in mice, resulting in reduced muscle mass, strength, and the number of blood vessels”

    Animalsdietary supplementation2%

    Microbiota derived D-malate inhibits skeletal muscle growth and angiogenesis during aging via acetylation of Cyclin A

    EMBO reports22 Jan 2024

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