Cytotoxic cancer therapy

Cytotoxic cancer therapy has been studied in 1 paper since 2026: 1 observational study in people; 1 in the past year. The newest story, Nov 9, 2026: “Breast cancer therapy linked to shifts in mutated blood cells”.

Exposure

1 paper studies it2 findingsUpdated Jun 9, 2026

See all 1 papers on cytotoxic cancer therapy

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“cytotoxic treatments led to strong therapeutic bottlenecks, resulting in significant reductions in hematopoietic allelic populations”

Evolution of clonal hematopoiesis during cancer treatment and its impact on outcomesThe Journal of clinical investigation2026doi:10.1172/jci204429

None of its findings points the other way.

1 lab in 1 country

Funders: Breast Cancer Research Foundation and 4 more
2 of 2 findings with company ties

Humans1

What did studies of cytotoxic cancer therapy find?

Studies of cytotoxic cancer therapy measured 2 outcomes: positively selected clonal hematopoiesis and Hematopoietic allelic populations.

Positively selected clonal hematopoiesis

upin humans1

1 study

Cytotoxic cancer therapy is linked with positively selected clonal hematopoiesis in humans (through dose-dependent therapeutic bottlenecks).
“Positively selected CH that expanded through dose-dependent therapeutic bottlenecks”
Humansthrough dose-dependent therapeutic bottlenecks
Breast cancer therapy linked to shifts in mutated blood cells
The Journal of clinical investigationJun 9, 2026

More on Positively selected clonal hematopoiesis

Hematopoietic allelic populations

downin humans1

1 study

Cytotoxic cancer therapy is linked with lower hematopoietic allelic populations in patients with breast cancer during treatment.
“cytotoxic treatments led to strong therapeutic bottlenecks, resulting in significant reductions in hematopoietic allelic populations”
Humansin patients with breast cancer during treatment
Breast cancer therapy linked to shifts in mutated blood cells
The Journal of clinical investigationJun 9, 2026

Latest

1 paper in 12 months

The Journal of Clinical InvestigationJun 9

Breast cancer therapy linked to shifts in mutated blood cells

An observational study of 171 women linked expanding groups of mutated blood-forming cells during treatment to shorter survival than stable or shrinking groups.An observational study of 171 women linked expanding groups of mutated blood-forming cells during treatment to shorter survival than stable or shrinking groups.

Cohort · 171 peopleMechanisms

Paper