The Journal of Clinical Investigation
Breast cancer therapy linked to shifts in mutated blood cells
An observational study of 171 women linked expanding groups of mutated blood-forming cells during treatment to shorter survival than stable or shrinking groups.An observational study of 171 women linked expanding groups of mutated blood-forming cells during treatment to shorter survival than stable or shrinking groups.
Cohort · 171 peopleMechanisms
Who was studied171 women with breast cancer, against women receiving hormone therapy
What changedThe mix of blood-forming cells narrowed more with chemotherapy than with hormone therapy
The catchBlood-cell population restrictions were model estimates, not direct cell counts