Cpd 60
1 paper2 findings
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Animals1
Outcomes
2Inflammation
downin mice1
1 study
Inflammation
downin mice1
Cpd 60 decreases inflammation in mice.
“HDAC1 antagonism by Cpd 60 reduced the mitochondrial dysfunction and improved aging-related inflammation, as validated in D-galactose treated APN KO mice.”
AnimalsD-galactose treated APN KO mice
APN deficiency accelerates brain aging via mitochondrial associated neuroinflammation
Research SquareApr 20, 2022Preprint
Mitochondrial dysfunction
downin mice1
1 study
Mitochondrial dysfunction
downin mice1
Cpd 60 decreases mitochondrial dysfunction in mice.
“HDAC1 antagonism by Cpd 60 reduced the mitochondrial dysfunction and improved aging-related inflammation, as validated in D-galactose treated APN KO mice.”
AnimalsD-galactose treated APN KO mice
APN deficiency accelerates brain aging via mitochondrial associated neuroinflammation
Research SquareApr 20, 2022Preprint
Latest
Research Square
APN deficiency accelerates brain aging via mitochondrial associated neuroinflammation
Preprint: experiments in miceInflammation