Continuous fermentation

1. Continuous fermentation increases nicotinamide mononucleotide in E. coli cells (4.14–4.26 g/L/h).

   “In contrast, the highest productivity of 4.14–4.26 g/L/h was observed at D = 0.3 h−1, despite a decrease in NMN concentration to 13.8–14.2 g/L.”

   Cellsat D = 0.3 h−1

   Continuous production of nicotinamide mononucleotide by engineered Escherichia coli: effect of dilution rate and glucose feeding

   Bioprocess and biosystems engineering·26 Mar 2026

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