Complex mental activities
1 paper4 findings
- 1 lab in 1 country
- Funders: National Institute of Neurological Disorders and Stroke and 2 more
- Humans1
Outcomes
1Tau burden
no changein humans1
1 study
Tau burden
no changein humans1
Complex mental activities have no effect on tau burden in humans.
“There were no associations between complex mental activities and tau burden.”
Humansbrainn = 76
Neurobiology of aging30 Jun 2026
Associations
3Locus coeruleus integrity
upin humans1
1 study
Locus coeruleus integrity
upin humans1
Complex mental activities are associated with locus coeruleus integrity in humans.
“overall higher levels of complex mental activities were associated with larger estimates of gray matter volume and cortical thickness in the cingulate cortex and higher integrity of the LC”
Humanslocus coeruleusn = 60
Neurobiology of aging30 Jun 2026
Cortical thickness
upin humans1
1 study
Cortical thickness
upin humans1
Complex mental activities are associated with cortical thickness in humans.
“overall higher levels of complex mental activities were associated with larger estimates of gray matter volume and cortical thickness in the cingulate cortex”
Humanscingulate cortexn = 76
Neurobiology of aging30 Jun 2026
Gray matter volume
upin humans1
1 study
Gray matter volume
upin humans1
Complex mental activities are associated with gray matter volume in humans.
“overall higher levels of complex mental activities were associated with larger estimates of gray matter volume and cortical thickness in the cingulate cortex”
Humanscingulate cortexn = 76
Neurobiology of aging30 Jun 2026
Latest
1 in 12 monthsNeurobiology of Aging
Brain structure in the cingulate cortex and locus coeruleus in late life is associated with engagement in complex mental activities across the life span
Cohort study of 76 peoplePopulations