Locus coeruleus integrity

1. Locus coeruleus integrity is associated with slow waves in humans.

   “Higher LC integrity was associated with greater slow-wave activity and slow oscillation power, with stronger effects in females.”

   Humansbrain

   Relationship between locus coeruleus and slow-wave sleep in aging and Alzheimer's disease

   Alzheimer's & dementia : the journal of the Alzheimer's Association·1 Feb 2026

More on Slow waves

1. Locus coeruleus integrity is associated with visual short-term memory binding accuracy in humans (b=7.10, p = .010).

   “Lower rostral‐middle, but not caudal, LC‐CNR was associated with poorer SCB accuracy relative to SO condition accuracy (b=7.10, p = .010).”

   Humanscognitively unimpairedrostral‐middle locus coeruleusmales

   Visual short‐term memory binding, locus coeruleus integrity, and subjective cognitive decline in cognitively unimpaired older adults

   AAIC 2025 abstract·26 Dec 2025