Clozapine-induced microglial exosomes

Clozapine-induced microglial exosomes has been studied in 1 paper since 2026: 1 observational study in people; 1 in the past year. The newest paper, Apr 20, 2026: “Clozapine-induced human microglial exosomes impair neurites and cognition”.

Intervention

1 paper studies it3 findingsUpdated

  • 1 lab in 1 country
  • Funder: National Health and Medical Research Council
  • Humans1

What did studies of Clozapine-induced microglial exosomes find?

3

Studies of Clozapine-induced microglial exosomes measured 3 outcomes; the most studied are cognitive function (1 study), lifespan (1) and BDNF (1).

Cognitive function

downin worms1

1 study
  1. Clozapine-induced microglial exosomes impair cognitive function in worms.

    “In C. elegans, clozapine-induced exosomes reduced lifespan and severely impaired learning and short-term memory.”

    Model organismsexposure to clozapine-induced microglial exosomes

    Clozapine-induced human microglial exosomes impair neurites and cognition

    Brain, behavior, and immunity

Lifespan

downin worms1

1 study
  1. Clozapine-induced microglial exosomes shorten lifespan in worms.

    “In C. elegans, clozapine-induced exosomes reduced lifespan and severely impaired learning and short-term memory.”

    Model organismsexposure to clozapine-induced microglial exosomes

    Clozapine-induced human microglial exosomes impair neurites and cognition

    Brain, behavior, and immunity

BDNF

downin mouse cells1

1 study
  1. Clozapine-induced microglial exosomes decrease BDNF in mouse cells.

    “Exposure of neurons to clozapine-induced exosomes reduced neurite length, branch points, and BDNF expression.”

    Cellsexposure to clozapine-induced microglial exosomes

    Clozapine-induced human microglial exosomes impair neurites and cognition

    Brain, behavior, and immunity

More on BDNF

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months