Potassium citrate + citric acid

Potassium citrate + citric acid has been studied in 1 paper since 2000: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Nov 1, 2000: “Citrate therapy for polycystic kidney disease in rats”.

Intervention

1 paper studies it2 findingsUpdated

PubChemPubChemChEBIChEBI

None of its findings points the other way.

  • 1 lab
  • Animals1

What did studies of Potassium citrate + citric acid find?

2

Studies of Potassium citrate + citric acid measured 2 outcomes; the most studied are lifespan (1 study) and glomerular filtration rate (1).

Lifespan

upin rats1

1 study
  1. Potassium citrate + citric acid extends lifespan in rats (from 10 to 17 months).

    “Long-term KCitr treatment extended the average life span of rats with PKD from 10 to 17 months.”

    Animalspolycystic kidney diseasemales

    Citrate therapy for polycystic kidney disease in rats

    Kidney international

Glomerular filtration rate

upin rats1

1 study
  1. Potassium citrate + citric acid improves glomerular filtration rate in rats (normal vs one third of normal).

    “The GFRs of rats with PKD that consumed KCitr from one month of age were normal at six months of age, while those of their counterparts on water were about one third of normal.”

    Animalspolycystic kidney diseasekidneymales

    Citrate therapy for polycystic kidney disease in rats

    Kidney international

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