Central fluid percussion injury

1. Central fluid percussion injury increases mature oligodendrocytes in mice.

   “male mice showed a robust increase in newly generated mature oligodendrocytes within their white matter tracts, TBI did not induce comparable oligodendrogenesis in females.”

   AnimalscFPI model of diffuse TBI, 30 dpiwhite matter tractsmales

   Age- and sex-dependent differences in white matter pathology in the chronic phase of diffuse traumatic brain injury in the mouse

   Experimental neurology·5 Apr 2026

More on Mature oligodendrocytes

1. Central fluid percussion injury increases inflammation in mice.

   “Regardless of age, male mice exhibited a more pronounced inflammatory response compared to females, characterized by a greater Ionized calcium-binding adaptor molecule 1 (Iba1) coverage”

   AnimalscFPI model of diffuse TBI, 30 dpibrain white matter

   Age- and sex-dependent differences in white matter pathology in the chronic phase of diffuse traumatic brain injury in the mouse

   Experimental neurology·5 Apr 2026

More on Inflammation