AgingResearch.NewsJoin free

Cecal microbiota transplantation

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Against: findings that point the other way from most findings on the same outcome.

  • 1 lab in 1 country
  • 1 finding against
  • Funders: National Heart, Lung, and Blood Institute and 1 more
  • Animals1

Outcomes

2

Systolic blood pressure

no changein rats1upin rats1

1 study

  1. Cecal microbiota transplantation has no effect on systolic blood pressure in rats.

    “Systolic BP of the R rats remained unaltered irrespective of S or R rat cecal transplantation.”

    Animalsin Dahl salt-resistant (R) rats maintained on a high-salt diet following microbiota ablation with antibiotics

    Evidence for a link between gut microbiota and hypertension in the Dahl rat

    Physiological genomics31 Mar 2015

  2. Cecal microbiota transplantation increases systolic blood pressure in rats.

    “systolic BP of the S rats given a single bolus of cecal content from R rats was consistently and significantly elevated during the rest of their life”

    Animalsin Dahl salt-sensitive (S) rats maintained on a high-salt diet following microbiota ablation with antibioticssingle bolus

    Evidence for a link between gut microbiota and hypertension in the Dahl rat

    Physiological genomics31 Mar 2015

More on Systolic blood pressure

Lifespan

downin rats1

1 study

  1. Cecal microbiota transplantation shortens lifespan in rats.

    “they had a shorter lifespan”

    Animalsin Dahl salt-sensitive (S) rats maintained on a high-salt diet following microbiota ablation with antibioticssingle bolus

    Evidence for a link between gut microbiota and hypertension in the Dahl rat

    Physiological genomics31 Mar 2015

Latest

Related