CD47 aso

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funders: National Institute of Diabetes and Digestive and Kidney Diseases and 3 more
  • 4 of 4 findings with company ties
  • Animals1

Outcomes

4

Hyperlipidemia

downin mice1

1 study
  1. CD47 aso decreases hyperlipidemia in mice.

    “improved glucose tolerance, insulin sensitivity, and hyperlipidemia”

    Animals25 μg/g10 weeksmales

    CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice

    Aging1 Dec 2025

More on Hyperlipidemia

Glucose tolerance

upin mice1

1 study
  1. CD47 aso improves glucose tolerance in mice.

    “It also improved glucose tolerance, insulin sensitivity, and hyperlipidemia”

    Animals25 μg/g10 weeksmales

    CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice

    Aging1 Dec 2025

Body weight

no changein mice1

1 study
  1. CD47 aso has no effect on body weight in mice.

    “without affecting overall body weight in aged mice.”

    Animals25 μg/g10 weeksmales

    CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice

    Aging1 Dec 2025

Visceral adiposity

downin mice1

1 study
  1. CD47 aso decreases visceral adiposity in mice.

    “CD47ASO treatment selectively reduced visceral adiposity without affecting overall body weight in aged mice.”

    Animals25 μg/g10 weeksmales

    CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice

    Aging1 Dec 2025

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