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CD24FC

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Medpace and 4 more
  • 2 of 2 findings with company ties
  • Human trial1

Outcomes

2

Inflammation

downin humans1

1 study

  1. CD24FC inhibits inflammation in humans.

    “A first-in-human study of CD24Fc (NCT02650895) supports the significance of this pathway in human lipid metabolism and inflammation.”

    Human trialNCT02650895

    CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder

    Cell metabolismAug 1, 2022

More on Inflammation

Metabolic disorders

downin mice1

1 study

  1. CD24FC decreases metabolic disorders in mice.

    “CD24Fc treatment alleviates, diet-induced metabolic disorders, including obesity, dyslipidemia, insulin resistance, and nonalcoholic steatohepatitis (NASH).”

    Animalsdiet-induced metabolic disorders

    CD24-Siglec axis is an innate immune checkpoint against metaflammation and metabolic disorder

    Cell metabolismAug 1, 2022

More on Metabolic disorders

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