Cataract extraction

Cataract extraction has been studied in 3 papers since 2021: 1 observational study in people, 2 reviews; 1 in the past year. The newest paper, Jan 16, 2026: “Mental disorders associated with cataract and its surgical treatment with intraocular lens implantation: a review”.

Exposure

3 papers study it3 findingsUpdated

MeSH

See all 3 papers on cataract extraction

At a glance

The findings reach people, from one lab or study. 1 lab in 1 country.

“cataract extraction was associated with significantly reduced risk (hazard ratio, 0.71; 95% CI, 0.62-0.83; P < .001) of dementia compared with participants without surgery”
Association Between Cataract Extraction and Development of DementiaJAMA internal medicine2021doi:10.1001/jamainternmed.2021.6990

None of its findings points the other way.

Humans: a single group. Cells, worms or flies and mice: nothing yet.
  • 1 lab in 1 country
  • Funders: National Eye Institute and 3 more
  • 2 of 2 findings with company ties
  • Humans1

What is cataract extraction linked with?

3

Studies link cataract extraction with 3 measures, most often mental disorders (1 study), Alzheimer's disease (1) and dementia (1).

Mental disorders

downin humans1

1 study
  1. Cataract extraction lowers the risk of mental disorders in cataract patients.

    “Cataract extraction reduces this risk, improves quality of life and sleep, and promotes favorable structural and functional changes in the cerebral cortex.”

    Reviewin cataract patients

    Mental disorders associated with cataract and its surgical treatment with intraocular lens implantation: a review

    Neurology Bulletin

More on Mental disorders

Alzheimer's disease

downin humans1

1 study
  1. Cataract extraction is linked with a lower risk of Alzheimer's disease in humans.

    “Similar results were found with the development of Alzheimer disease dementia.”

    Humansn = 3,038

    Association Between Cataract Extraction and Development of Dementia

    JAMA internal medicine

More on Alzheimer's disease

Dementia

downin humans1HR 0.71

1 study
  1. Cataract extraction is linked with a lower risk of dementia in humans (HR 0.71, 95% CI 0.62-0.83).

    “cataract extraction was associated with significantly reduced risk (hazard ratio, 0.71; 95% CI, 0.62-0.83; P < .001) of dementia compared with participants without surgery”

    Humansafter controlling for years of education, self-reported White race, and smoking history and stratifying by apolipoprotein E genotype, sex, and age group at cataract diagnosis23 554 person-years of follow-upn = 3,038

    Association Between Cataract Extraction and Development of Dementia

    JAMA internal medicine

More on Dementia

Latest

Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 01 paper in 12 months