Calvarial bone marrow secretome
1 paper2 findings
- 1 lab in 1 country
- Funders: National Institute of Neurological Disorders and Stroke and 1 more
- Animals1
Outcomes
2Mitochondrial membrane potential
downin mouse cells1
1 study
Mitochondrial membrane potential
downin mouse cells1
Calvarial bone marrow secretome decreases mitochondrial membrane potential in mouse cells.
“skull-derived secretome factors impaired cortical and hippocampal mitochondrial metabolism, and reduced microglial mitochondrial membrane potential.”
CellsSecretome from bone marrow exposed to repetitive head impactsSkull-derived secretome factorsMicroglia
Repeated head impacts establish a senescent cranial bone marrow niche that impairs brain metabolism
Journal of neuroinflammation27 May 2026
Cortical and hippocampal mitochondrial metabolism
downin mouse cells1
1 study
Cortical and hippocampal mitochondrial metabolism
downin mouse cells1
Calvarial bone marrow secretome impairs cortical and hippocampal mitochondrial metabolism in mouse cells.
“skull-derived secretome factors impaired cortical and hippocampal mitochondrial metabolism”
CellsSecretome from bone marrow exposed to repetitive head impactsSkull-derived secretome factorsCortex and hippocampus
Repeated head impacts establish a senescent cranial bone marrow niche that impairs brain metabolism
Journal of neuroinflammation27 May 2026