Budesonide

Intervention

1 paper3 findings

PubChemChEBI

  • 1 lab
  • Humans1

Outcomes

1

Estimated glomerular filtration rate

no changein humans1

1 study
  1. Budesonide has no effect on estimated glomerular filtration rate in humans.

    “eGFR was stable across the treatment period, with no significant change from baseline at nine months or at latest follow-up.”

    HumansBiopsy-proven IgA nephropathy with near-universal RAS and SGLT2 inhibitor usetargeted-release formulationNine months and latest follow-up (median 11.2 months)n = 33

    RealxWorld Effectiveness of Targeted-Release Budesonide in IgA Nephropathy with Near-Universal SGLT2 Inhibitor Use

    American journal of nephrology15 Oct 2026

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Associations

2

Adverse effects

upin humans1

1 study
  1. Budesonide is associated with adverse effects in humans (9 of 33 patients (27%) had a recorded adverse effect).

    “An adverse effect was recorded in 9 of 33 patients (27%).”

    HumansBiopsy-proven IgA nephropathy; retrospective ascertainmenttargeted-release formulationMedian follow-up 11.2 monthsn = 33

    RealxWorld Effectiveness of Targeted-Release Budesonide in IgA Nephropathy with Near-Universal SGLT2 Inhibitor Use

    American journal of nephrology15 Oct 2026

Urine protein-to-creatinine ratio

downin humans1

1 study
  1. Budesonide is associated with urine protein-to-creatinine ratio in humans (60% decrease (IQR 31–71%) in the intention-to-treat cohort).

    “UPCR decreased by 60% (IQR 31-71%) in the ITT cohort (p < 0.001)”

    HumansBiopsy-proven IgA nephropathy; RAS inhibitor use 94% and SGLT2 inhibitor use 91%targeted-release formulationMedian 11.2 monthsn = 33

    RealxWorld Effectiveness of Targeted-Release Budesonide in IgA Nephropathy with Near-Universal SGLT2 Inhibitor Use

    American journal of nephrology15 Oct 2026

More on Urine protein-to-creatinine ratio

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