BMP4
BMP4 has been studied in 4 papers since 2016: none in people yet, 4 in cells; 2 in the past year. No study of it in people or animals has been published yet. The newest paper, Mar 23, 2026: “Refining fibroblast-to-cardiomyocyte transdifferentiation protocols to explore emergent self-organization in cardiac cultures”.
4 papers study it2 findingsUpdated
At a glance
The findings reach cells, none yet in people. 1 lab in 2 countries.
1 of its findings points the other way.
- 1 lab in 2 countries
- 1 finding against
- Funders: Japan Society for the Promotion of Science and 4 more
- 2 of 2 findings with company ties
- Cells4
What did studies of BMP4 find?
1Studies of BMP4 measured one outcome, iPSC generation.
iPSC generation
downin human cells1upin human cells1
1 study
iPSC generation
downin human cells1upin human cells1
BMP4 decreases iPSC generation in human cells (later times during reprogramming).
“adding BMP4 at later times decreased iPSC generation”
Cellslater times during reprogramming
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence
Proceedings of the National Academy of Sciences of the United States of America
BMP4 increases iPSC generation in human cells (early times during reprogramming).
“the efficiency of iPSC generation was enhanced by transducing mutant ACVR1 (617G > A) or SMAD1 or adding BMP4 protein at early times during the reprogramming”
Cellsearly times during reprogramming
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence
Proceedings of the National Academy of Sciences of the United States of America