Blackcurrant formula

1. Blackcurrant formula decreases circulating neurotransmitter metabolites in humans.

   “These changes corresponded with significant reductions (q < 0.05) in circulating neurotransmitter metabolites xanthurenic acid, 3-methoxy-4-hydroxyphenylglycol and vanillylmandelic acid.”

   Human trialHealthy older adultsBeverageBloodSingle doseAcuten = 26

   Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study

   Frontiers in pharmacology·30 Sep 2026

More on Circulating neurotransmitter metabolites

1. Blackcurrant formula decreases biomarkers of monoamine oxidase activity in humans.

   “Reduction in biomarkers of MAO activity were measured following acute supplementation with BCF, but not placebo, with significant treatment × time interactions (q < 0.01)”

   Human trialHealthy older adults; compared with placeboBeverageBloodSingle doseAcuten = 26

   Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study

   Frontiers in pharmacology·30 Sep 2026

More on Biomarkers of monoamine oxidase activity

1. Blackcurrant formula decreases mental fatigue in humans.

   “a strong trend in reduced mental fatigue (p = 0.046, q = 0.067) were measured following 4 weeks of BCF supplementation.”

   Human trialHealthy older adults; reported as a trendBeverageDaily4 weeksn = 26

   Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study

   Frontiers in pharmacology·30 Sep 2026

1. Blackcurrant formula decreases rapid Visual Information Processing false alarms in humans.

   “A significant reduction in Rapid Visual Information Processing (RVIP) false alarms (p = 0.022)”

   Human trialHealthy older adultsBeverageDaily4 weeksn = 26

   Four-week supplementation with a blackcurrant formulation enhances cognitive performance, reduces mental fatigue and modulates peripheral monoamine metabolism in older adults: a randomized, double-blind, placebo-controlled, crossover study

   Frontiers in pharmacology·30 Sep 2026