Bisphenol a + sucralose

  • 1 lab in 1 country
  • Funder: Foundation for Science and Technology
  • Model organisms1

Outcomes

4

DNA strand breaks

upin flies1

1 study
  1. Bisphenol a + sucralose increases DNA strand breaks in flies.

    “DNA damage confirmed that exposure increases DNA strand breaks”

    Model organismsco-exposure to BPA and sucralose

    Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in Drosophila melanogaster

    International journal of molecular sciences28 May 2026

More on DNA strand breaks

Locomotor behavior

downin flies1

1 study
  1. Bisphenol a + sucralose impairs locomotor behavior in flies (from 60 s in the control group to 0.67 s in treated larvae).

    “neurobehavioral tests revealed impaired locomotion, with a decrease in movement from 60 s in the control group to 0.67 s in treated larvae”

    Model organismsco-exposure to BPA and sucralose

    Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in Drosophila melanogaster

    International journal of molecular sciences28 May 2026

Body weight

downin flies1

1 study
  1. Bisphenol a + sucralose decreases body weight in flies.

    “co-exposure to BPA and sucralose induces a significant reduction in prolificity at 0.5 mM BPA (50% at the highest concentrations), as well as in body weight”

    Model organismsco-exposure to BPA and sucralose

    Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in Drosophila melanogaster

    International journal of molecular sciences28 May 2026

Lifespan

downin flies1

1 study
  1. Bisphenol a + sucralose shortens lifespan in flies (54 days vs. 89 days in the control group).

    “co-exposure to BPA and sucralose induces a significant reduction in prolificity at 0.5 mM BPA (50% at the highest concentrations), as well as in body weight and lifespan”

    Model organismsco-exposure to BPA and sucralose

    Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in Drosophila melanogaster

    International journal of molecular sciences28 May 2026

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