Levamlodipine + bisoprolol

1. Levamlodipine + bisoprolol protects against stroke in rats.

   “Combined use of levamlodipine and bisoprolol produced better protection against stroke.”

   Animalsin stroke-prone rats

   Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats

   CNS neuroscience & therapeutics·1 Mar 2013

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1. Levamlodipine + bisoprolol decreases infarct area in rats.

   “The infarct area was the smallest in subjects receiving drug combination in SD rats both with and without SAD.”

   Animalsin SD rats with and without SAD subjected to MCAO

   Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats

   CNS neuroscience & therapeutics·1 Mar 2013

1. Levamlodipine + bisoprolol extends lifespan in rats.

   “the lifespan of SHR-SP rats exposed to the drug combination was longer than that in rats exposed to either drug alone.”

   Animalsin SHR-SPdietary admixture (via food)

   Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats

   CNS neuroscience & therapeutics·1 Mar 2013

1. Levamlodipine + bisoprolol decreases systolic blood pressure in rats.

   “SBP was significantly reduced by combination therapy both in SHR-SP and SAD rats.”

   Animalsin SHR-SP and SAD rats

   Effects of combination therapy with levamlodipine and bisoprolol on stroke in rats

   CNS neuroscience & therapeutics·1 Mar 2013

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