Beta-aminoisobutyric acid

Intervention1 paper2 findingsPubChem 64956ChEBI 27389

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

1 lab
  • Animals1

Outcomes

2

Muscle dysfunction

downin mice1

1 study
  1. Beta-aminoisobutyric acid decreases muscle dysfunction in mice.

    Animalsin a mouse model of diabetes

    The metabokine β-aminoisobutyric acid mediates exercise performance and skeletal muscle adaptation through a PGC1α-BAIBA-PPARδ axis · Nature communications · 18 Aug 2026

Exercise performance

upin mice1

1 study
  1. Beta-aminoisobutyric acid improves exercise performance in mice.

    Animalsvia PPARδ

    The metabokine β-aminoisobutyric acid mediates exercise performance and skeletal muscle adaptation through a PGC1α-BAIBA-PPARδ axis · Nature communications · 18 Aug 2026

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