Bempedoic acid-based therapy

Bempedoic acid-based therapy has been studied in 1 paper since 2026: 1 observational study in people; 1 in the past year. The newest paper, Oct 26, 2026: “Predicted change in 10-year cardiovascular risk one year after initiation of bempedoic acid-based therapy in the MILOS study”.

Intervention

1 paper studies it2 findingsUpdated

1 new paper in 30 daysSee all 1

“Mean LDL-C reduction from pre-treatment to 1-year follow-up was 0.88 mmol/L”
Predicted change in 10-year cardiovascular risk one year after initiation of bempedoic acid-based therapy in the MILOS studyESC Congress 2026 abstract2026doi:10.1093/eurheartj/ehag785.3391
  • 1 lab in 1 country
  • 1 of 1 finding with company ties
  • Humans1

What is Bempedoic acid-based therapy linked with?

2

Studies link Bempedoic acid-based therapy with 2 measures, most often predicted 10-year cardiovascular risk (1 study) and LDL cholesterol (1).

Predicted 10-year cardiovascular risk

downin silico1

1 study
  1. Bempedoic acid-based therapy is associated with predicted 10-year cardiovascular risk in silico (Modeled translation of observed LDL-C reductions, assuming sustained LDL-C lowering) (Estimated absolute risk reduction 4.8% (SD 6.7); relative risk reduction 17.1% (SD 20.5)).

    “an estimated ARR of 4.8% in 10-year CV risk (SD 6.7; Figure) or a RRR of 17.1% (SD 20.5)”

    In silicoModeled translation of observed LDL-C reductions, assuming sustained LDL-C lowering10-year prediction based on 1-year LDL-C changesn = 960

    Predicted change in 10-year cardiovascular risk one year after initiation of bempedoic acid-based therapy in the MILOS study

    ESC Congress 2026 abstract

More on Predicted 10-year cardiovascular risk

LDL cholesterol

downin humans1

1 study
  1. Bempedoic acid-based therapy is associated with LDL cholesterol in humans (−0.88 mmol/L from pretreatment to 1 year).

    “Mean LDL-C reduction from pre-treatment to 1-year follow-up was 0.88 mmol/L”

    HumansPrimary hypercholesterolemia or mixed dyslipidemia; bempedoic acid alone or in fixed-dose combination with ezetimibe1 yearn = 960

    Predicted change in 10-year cardiovascular risk one year after initiation of bempedoic acid-based therapy in the MILOS study

    ESC Congress 2026 abstract

More on LDL cholesterol

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Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 11 paper in 12 months