Autologous basal cell transplantation

1. Autologous basal cell transplantation improves pulmonary function in humans.

   “Autologous BCs transplantation in three advanced IPF patients with small airway dysfunction yielded significant clinical improvements in pulmonary function, particularly evidence in lung volume and small airway function.”

   Human trialadvanced IPF with small airway dysfunctionn = 3

   Epithelial stem cells from human small bronchi offer a potential for therapy of idiopathic pulmonary fibrosis

   EBioMedicine·2 Jan 2025

1. Autologous basal cell transplantation protects against pulmonary fibrosis in mice.

   “In a mouse model of pulmonary fibrosis, BCs exhibited promising protective efficacy and safety for transplantation therapy.”

   Animalsin mouse model of pulmonary fibrosis

   Epithelial stem cells from human small bronchi offer a potential for therapy of idiopathic pulmonary fibrosis

   EBioMedicine·2 Jan 2025

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