Astragalus polysaccharide

Intervention

1 paper studies it5 findings

Across all fields, 1 paper: none in people yet, 1 in animals

  • 1 lab in 1 country
  • Model organisms1

Outcomes

5

Neurobehavioral deficits

no changein flies1

1 study
  1. Astragalus polysaccharide has no effect on neurobehavioral deficits in flies.

    “without rescuing neurobehavioral deficits in the AD model of taupathy and Parkinson's disease (PD) model of Pink1 mutation”

    Model organismsin tauopathy AD and Pink1 mutation PD models

    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster

    International journal of biological macromolecules

Motility

upin flies1

1 study
  1. Astragalus polysaccharide improves motility in flies.

    “APS supplementation delayed the onset of Alzheimer's phenotypes in Aβ42-induced Alzheimer's disease (AD) flies, including the extension of lifespan and the increase in motility”

    Model organismsin Aβ42-induced Alzheimer's disease (AD) flies

    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster

    International journal of biological macromolecules

Lifespan

upin flies1

1 study
  1. Astragalus polysaccharide extends lifespan in flies.

    “APS supplementation delayed the onset of Alzheimer's phenotypes in Aβ42-induced Alzheimer's disease (AD) flies, including the extension of lifespan and the increase in motility”

    Model organismsin Aβ42-induced Alzheimer's disease (AD) flies

    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster

    International journal of biological macromolecules

Sleep disorders

downin flies1

1 study
  1. Astragalus polysaccharide decreases sleep disorders in flies.

    “administration of APS significantly attenuated age-associated disruption of the intestinal barrier, loss of gastrointestinal acid-base balance, reduction in intestinal length, overproliferation of the intestinal stem cells (ISCs), and sleeping disorders upon aging.”

    Model organismsupon aging

    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster

    International journal of biological macromolecules

Intestinal barrier disruption

downin flies1

1 study
  1. Astragalus polysaccharide decreases intestinal barrier disruption in flies.

    “administration of APS significantly attenuated age-associated disruption of the intestinal barrier”

    Model organismsupon aging

    Regulation and mechanism of Astragalus polysaccharide on ameliorating aging in Drosophila melanogaster

    International journal of biological macromolecules

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