Anxa1− cd8+ naïve t cell transfer
1 paper5 findings
- 1 lab in 1 country
- Funder: National Natural Science Foundation of China
- Animals1
Outcomes
5Motor coordination
upin mice1
1 study
Motor coordination
upin mice1
Anxa1− cd8+ naïve t cell transfer improves motor coordination in mice.
“improving cardiac function, bone density, motor coordination, and marrow immune microenvironment.”
Animalssyngeneic ANXA1− CD8+ naïve T cellsmonthly transfer
Transplanting ANXA1⁻ CD8⁺ Naïve T cells Delay Aging Through Senolysis
bioRxiv (Cold Spring Harbor Laboratory)23 Feb 2026Preprint
Cardiac function
upin mice1
1 study
Cardiac function
upin mice1
Anxa1− cd8+ naïve t cell transfer improves cardiac function in mice.
“improving cardiac function, bone density, motor coordination, and marrow immune microenvironment.”
Animalssyngeneic ANXA1− CD8+ naïve T cellsheartmonthly transfer
Transplanting ANXA1⁻ CD8⁺ Naïve T cells Delay Aging Through Senolysis
bioRxiv (Cold Spring Harbor Laboratory)23 Feb 2026Preprint
Lifespan
upin mice1
1 study
Lifespan
upin mice1
Anxa1− cd8+ naïve t cell transfer extends lifespan in mice (>30 weeks longer median lifespan).
“Monthly transfer of syngeneic ANXA1− CD8+ naïve T cells into aged mice extended median lifespan by >30 weeks”
Animalssyngeneic ANXA1− CD8+ naïve T cellsmonthly transfer
Transplanting ANXA1⁻ CD8⁺ Naïve T cells Delay Aging Through Senolysis
bioRxiv (Cold Spring Harbor Laboratory)23 Feb 2026Preprint
Senescence burden
downin mice1
1 study
Senescence burden
downin mice1
Anxa1− cd8+ naïve t cell transfer decreases senescence burden in mice.
“ANXA1− cells showed senolytic activity in vitro and reduced senescence burden in vivo”
Animalsin vivo
Transplanting ANXA1⁻ CD8⁺ Naïve T cells Delay Aging Through Senolysis
bioRxiv (Cold Spring Harbor Laboratory)23 Feb 2026Preprint
Senolysis
upin cells1
1 study
Senolysis
upin cells1
Anxa1− cd8+ naïve t cell transfer induces senolysis in cells.
“ANXA1− cells showed senolytic activity in vitro”
Cellsin vitro
Transplanting ANXA1⁻ CD8⁺ Naïve T cells Delay Aging Through Senolysis
bioRxiv (Cold Spring Harbor Laboratory)23 Feb 2026Preprint