Anticholinergic agents
Intervention1 paper3 findings
- Humans1
Outcomes
2Electronic frailty index
no changein humans1Low certainty
1 study
Electronic frailty index
no changein humans1Low certainty
Anticholinergic agents have no effect on electronic frailty index in humans.
Humanscompared with β3-agonist use in overactive bladder5 yearsfemales
Anticholinergics link to higher dementia risk in older women · International journal of urology : official journal of the Japanese Urological Association · 1 Oct 2026
Long-term care needs
no changein humans1HR 1.03Low certainty
1 study
Long-term care needs
no changein humans1HR 1.03Low certainty
Anticholinergic agents have no effect on long-term care needs in humans (HR 1.03, 95% CI 0.87-1.22).
Humanscompared with β3-agonist use in overactive bladderfemales
Anticholinergics link to higher dementia risk in older women · International journal of urology : official journal of the Japanese Urological Association · 1 Oct 2026
Associations
1Dementia
upin humans1HR 1.49Low certainty
1 study
Dementia
upin humans1HR 1.49Low certainty
Anticholinergic agents raise the risk of dementia in humans (HR 1.49, 95% CI 1.04-2.13).
Humanscompared with β3-agonist use in overactive bladderfemales
Anticholinergics link to higher dementia risk in older women · International journal of urology : official journal of the Japanese Urological Association · 1 Oct 2026
Latest
1Anticholinergics link to higher dementia risk in older women
Anticholinergic use was associated with higher incident dementia risk compared with β3-agonist use (hazard ratio, 1.49; 95% CI, 1.04–2.13).Anticholinergic use was associated with higher incident dementia risk compared with β3-agonist use (hazard ratio, 1.49; 95% CI, 1.04–2.13).