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Antibody-mediated γδ t-cell depletion

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: China Postdoctoral Science Foundation and 6 more
  • Animals1

Outcomes

1

Tumor metastatic foci

downin mice1

1 study

  1. Antibody-mediated γδ t-cell depletion decreases tumor metastatic foci in mice.

    “Accordingly, antibody-mediated depletion of γδT or neutrophils reduces tumor metastatic foci in aged animals”

    Animalsmales

    Aging-induced immune microenvironment remodeling fosters melanoma in male mice via γδ17-Neutrophil-CD8 axis

    Nature communications30 Dec 2024

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