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ANTI-IL-18 antibody

Intervention

1 paper studies it1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Humans1

Outcomes

1

Sepsis symptoms

downin mice1

1 study

  1. ANTI-IL-18 antibody decreases sepsis symptoms in mice.

    “Treatment with NLRP3 inhibition (MCC950) and antibodies against IL-18 and IL-1β alleviated sepsis symptoms in aged mice”

    Animalscecal ligation and puncture-induced sepsis

    The role and mechanism of the NLRP3-IL-1β/IL-18 signaling axis in the progression of sepsis under an aging phenotype

    Life sciencesJun 16, 2025

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