Anthracycline-based chemotherapy

Anthracycline-based chemotherapy has been studied in 1 paper since 2025: 1 observational study in people; 1 in the past year. The newest paper, Nov 1, 2025: “Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma”.

Intervention

1 paper studies it4 findingsUpdated

“total lean mass decreased by 1.70 kg (95% CI -2.55 to -0.85, p = 0.0002)”
Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With LymphomaHematological oncology2025doi:10.1002/hon.70154

None of its findings points the other way.

  • 1 lab in 1 country
  • Funders: Danske Fysioterapeuter and 1 more
  • Humans1

What did studies of Anthracycline-based chemotherapy find?

4

Studies of Anthracycline-based chemotherapy measured 4 outcomes; the most studied are sit-to-stand performance (1 study), handgrip strength (1) and body fat percentage (1).

Sit-to-stand performance

upin humans1

1 study
  1. Anthracycline-based chemotherapy improves sit-to-stand performance in humans (+1.4 repetitions (95% CI 0.15 to 2.69, p = 0.03)).

    “Sit-To-Stand performance increased by 1.4 repetitions (95% CI 0.15 to 2.69, p = 0.03)”

    Human trialaggressive lymphoma6 monthsn = 58

    Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma

    Hematological oncology

Handgrip strength

downin humans1

1 study
  1. Anthracycline-based chemotherapy impairs handgrip strength in humans (-1.93 kg (95% CI -3.15 to -0.71, p = 0.002)).

    “handgrip strength decreased by 1.93 kg (95% CI -3.15 to -0.71, p = 0.002)”

    Human trialaggressive lymphoma6 monthsn = 58

    Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma

    Hematological oncology

Body fat percentage

upin humans1

1 study
  1. Anthracycline-based chemotherapy increases body fat percentage in humans (+2.3% (95% CI 1.19 to 3.41, p = 0.0001)).

    “body fat percentage increased by 2.3% (95% CI 1.19 to 3.41, p = 0.0001)”

    Human trialaggressive lymphoma6 monthsn = 58

    Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma

    Hematological oncology

More on Body fat percentage

Total lean mass

downin humans1

1 study
  1. Anthracycline-based chemotherapy decreases total lean mass in humans (-1.70 kg (95% CI -2.55 to -0.85, p = 0.0002)).

    “total lean mass decreased by 1.70 kg (95% CI -2.55 to -0.85, p = 0.0002)”

    Human trialaggressive lymphoma6 monthsn = 58

    Changes in Lean Muscle Mass, Muscle Strength, and Physical Performance Following First-Line Chemotherapy in Patients With Lymphoma

    Hematological oncology

More on Total lean mass

Latest

Nov 2025: 1Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 paper in 12 months