Anemarrhena asphodeloides polysaccharides

Intervention1 paper3 findings

  • Model organisms1

Outcomes

3

FOXO signalling

upin worms1Very low certainty

1 study
  1. Anemarrhena asphodeloides polysaccharides activate FOXO signalling in worms.

    Model organismsAAP50-2 treatment

    A homogalacturonan polysaccharide from Anemarrhena asphodeloides promotes longevity in Caenorhabditis elegans with involvement of DAF-16/FOXO · International journal of biological macromolecules · 8 Sep 2026

FOXO signalling →

Lipofuscin

downin worms1Very low certainty

1 study
  1. Anemarrhena asphodeloides polysaccharides decrease lipofuscin in worms (-44% to -65%).

    Model organisms50, 100, and 200 μg/mL

    A homogalacturonan polysaccharide from Anemarrhena asphodeloides promotes longevity in Caenorhabditis elegans with involvement of DAF-16/FOXO · International journal of biological macromolecules · 8 Sep 2026

Lipofuscin →

Lifespan

upin worms1+56% maximum lifespanVery low certainty

1 study
  1. Anemarrhena asphodeloides polysaccharides extend lifespan in worms (+56.3% maximum lifespan).

    Model organisms50, 100, and 200 μg/mL

    A homogalacturonan polysaccharide from Anemarrhena asphodeloides promotes longevity in Caenorhabditis elegans with involvement of DAF-16/FOXO · International journal of biological macromolecules · 8 Sep 2026

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