Amino-modified polystyrene nanoparticles

Amino-modified polystyrene nanoparticles has been studied in 1 paper since 2022: none in people yet, 1 in animals. The research so far is in animals. The newest paper, Jun 28, 2022: “Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in nematode Caenorhabditis elegans”.

Exposure

1 paper studies it4 findingsUpdated

None of its findings points the other way.

  • 1 lab in 1 country
  • Model organisms1

What did studies of Amino-modified polystyrene nanoparticles find?

4

Studies of Amino-modified polystyrene nanoparticles measured 4 outcomes; the most studied are locomotion behavior (1 study), TGF-β signaling (1) and insulin/IGF-1 signaling (1).

Locomotion behavior

downin worms1

1 study
  1. Amino-modified polystyrene nanoparticles impair locomotion behavior in worms.

    “PS-COOH, PS-SOOOH or PS-NH2 exposure (1 μg/L or 15 μg/L) caused more serious toxicity in reducing locomotion behavior”

    Model organisms1 μg/L or 15 μg/L

    Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in nematode Caenorhabditis elegans

    Chemosphere

TGF-β signaling

downin worms1

1 study
  1. Amino-modified polystyrene nanoparticles inhibit TGF-β signaling in worms.

    “PS-NH2 exposure (15 μg/L) caused a significant decline in lifespan by suppressed DAF-16/insulin signaling and shortened body length by inhibiting DBL-1/TGF β signaling.”

    Model organisms15 μg/L

    Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in nematode Caenorhabditis elegans

    Chemosphere

More on TGF-β signaling

Insulin/IGF-1 signaling

downin worms1

1 study
  1. Amino-modified polystyrene nanoparticles inhibit insulin/IGF-1 signaling in worms.

    “PS-NH2 exposure (15 μg/L) caused a significant decline in lifespan by suppressed DAF-16/insulin signaling”

    Model organisms15 μg/L

    Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in nematode Caenorhabditis elegans

    Chemosphere

More on Insulin/IGF-1 signaling

Lifespan

downin worms1

1 study
  1. Amino-modified polystyrene nanoparticles shorten lifespan in worms.

    “PS-NH2 exposure (15 μg/L) caused a significant decline in lifespan”

    Model organisms15 μg/L

    Exposure to nanopolystyrene and its 4 chemically modified derivatives at predicted environmental concentrations causes differently regulatory mechanisms in nematode Caenorhabditis elegans

    Chemosphere

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