AgingResearch.NewsJoin free

Ascorbic acid + alpha-tocopherol

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • 4 of 4 findings with company ties
  • Animals1

Outcomes

4

TERT

upin mice1

1 study

  1. Ascorbic acid + alpha-tocopherol increases TERT in mice.

    “Furthermore, the vaccine formulated in α-tocopherol + VitC led to decreased PD1 and increased TERT gene expression levels.”

    Animalsinactivated SARS-CoV-2 vaccinationspleentwo weeks post-vaccination

    Ascorbic Acid and α-Tocopherol in the Inactivated SARS-CoV-2 Vaccine Formulation: Induction of the Th1 Pattern in Aged Mice

    Viral immunologyAug 30, 2024

More on TERT

PDCD1

downin mice1

1 study

  1. Ascorbic acid + alpha-tocopherol decreases PDCD1 in mice.

    “Furthermore, the vaccine formulated in α-tocopherol + VitC led to decreased PD1 and increased TERT gene expression levels.”

    Animalsinactivated SARS-CoV-2 vaccinationspleentwo weeks post-vaccination

    Ascorbic Acid and α-Tocopherol in the Inactivated SARS-CoV-2 Vaccine Formulation: Induction of the Th1 Pattern in Aged Mice

    Viral immunologyAug 30, 2024

More on PDCD1

IgG2a/IgG1 ratio

upin mice1

1 study

  1. Ascorbic acid + alpha-tocopherol increases IgG2a/IgG1 ratio in mice.

    “our results exhibited a significant decrease and increase in specific total IgG and the IgG2a/IgG1 ratio, respectively.”

    Animalsinactivated SARS-CoV-2 vaccinationtwo weeks post-vaccination

    Ascorbic Acid and α-Tocopherol in the Inactivated SARS-CoV-2 Vaccine Formulation: Induction of the Th1 Pattern in Aged Mice

    Viral immunologyAug 30, 2024

More on IgG2a/IgG1 ratio

Interferon-gamma

upin mice1

1 study

  1. Ascorbic acid + alpha-tocopherol increases interferon-gamma in mice.

    “IL-4 and IFN-γ cytokines showed a significant increase in both aged and young mice compared with the Alum-based vaccine.”

    Animalsinactivated SARS-CoV-2 vaccinationtwo weeks post-vaccination

    Ascorbic Acid and α-Tocopherol in the Inactivated SARS-CoV-2 Vaccine Formulation: Induction of the Th1 Pattern in Aged Mice

    Viral immunologyAug 30, 2024

More on Interferon-gamma

Latest

Related