AgingResearch.NewsJoin free

Alkaline ph

Exposure

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Canadian Institutes of Health Research and 2 more
  • Cells1

Outcomes

1

Heat shock response and chaperones

upin yeast cells1

1 study

  1. Alkaline ph activates heat shock response and chaperones in yeast cells.

    “We also found that growth at alkaline pH induces the activation of heat shock response (HSR) in young cells.”

    Cells

    Adjusting extracellular pH restores proteostasis and extends lifespan in a yeast model of polyglutamine toxicity

    bioRxiv (Cold Spring Harbor Laboratory)8 Sep 2025Preprint

More on Heat shock response and chaperones

Latest

Related